The guitarist and songwriter will play for the Teenage Cancer Trust, which he has long supported, at Royal Albert Hall on 25 and 26 March.
Other acts announced for the annual run of charity gigs include Arctic Monkeys, The Specials, Depeche Mode, JLS and reformed Britpop band Suede.
Gallagher left Oasis last year after an alleged backstage altercation with his brother, lead singer Liam.
Writing on the band's website last August, he said he "simply could not go on working with Liam a day longer".
Gallagher was the band's chief songwriter, and took lead vocals on some of their biggest hits - including Don't Look Back In Anger.
It is not known whether he will debut any new material at the shows in March, which have been billed as his only gigs of 2010